Leukaemia is a cancer of the white blood cells, which are produced by the bone marrow. There are two main types: lymphocytic leukaemia (arising from a type of white blood cell called a lymphocyte) and myeloid leukaemia (arising from an immature type of white blood cell called a myeloid stem cell).
The bone marrow produces two main types of white blood cells: granulocytes and lymphocytes. These work together to fight infection in the body. The fully developed white blood cells circulate around the body in the blood.Many patients with chronic leukemias are asymptomatic. Other leukemias present with splenomegaly, fever, weight loss, malaise, frequent infections, bleeding, thrombosis, or lymphadenopathy. Some chronic leukemias enter a blast phase where the clinical manifestations are similar to the acute leukemias.

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